Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea

Benefits and risks of the fish consumption should be assessed to balance ingestion healthy omega-3 fatty acids adverse chemicals. Persistent organic pollutants-POPs (organochlorine pesticides-OCPs polychlorinated biphenyls-PCB), macro- micro-elements acid contents were determined in six species from Adriatic Sea assess health for consumers (worst-case scenario, diseases development benefit-risk). 16 element, 24 POPs 14 pelagic which can used human diet. Element concentrations by inductively coupled plasma mass spectrometry (ICP-MS), high-resolution gas chromatography content gas–liquid chromatography. Diet based on chub mackerel round sardinella showed lower daily intake (DI) highest DI essential than other investigated species. Lower toxic elements observed consuming anchovy sardinella. Based POP concentrations, there was not non-carcinogenic (HI) nor carcinogenic (CR) consumers. element low HI (0.1 ? 1), while maximum HIs outlier values (horse samples) implied presence (HI > 1). The most significant contributor total inorganic arsenic (inorganic As). Acceptable CR assessed, but horse (CR 1 × 10–6) effects health. There developing cardiovascular, nervous, reproductive diseases, higher 1. (1 10 ?4 ?CR ?6 ) cancer nervous system organs. Among samples, those with ?BR (benefit-risks) BR (As) median value have a risk benefits • Consumers' chemicals fishes. intake-DI indicated c. r. as safe. lowest Horse had risk. Samples As more benefit